The complexity of cellular networks

7. Transcriptional regulation from
microarray data

  OUTLINE

• Brief overview of reverse engineering approaches
• Correlation and clustering microarray data
  • Predicting transcriptional regulation
  • Cause versus correlation
  • The "ARACNE" approach based un mutual information
  • The Context Likelihood of Relatedness method
• Boolean network approaches
• Approaches based on regression
  • Network identifiation by Multiple regression

 Lecture 7 (pdf) 

DEFINITIONS

PREVIOUS

NEXT