NetSciReg'15 - Network Models in Cellular Regulation
June 1, 2015 - Zaragoza, Spain

 NetSciReg'15 Flyer 
 Important Dates 
 Call for Contributed Talks 
 NetSci 2015 

Time: 3:00 - 3:40 PM

Type: Invited presentation

Affiliation: CNRS, Université de Lille Sciences et Technologies


Cellular regulatory networks often exhibit a sophisticated architecture made of many interlocked feedback loops operating at multiple timescales, even in the case of an a priori simple cellular function: a differentiation decision switch. In this presentation, I wish to discuss the notion that the complex design of differentiation regulatory network reflects various requirements, most likely related to the fact that the differentiation process competes or cooperates with other cellular processes (e.g.,alternative differentiation fates, proliferation, metabolism, cell-cell communication etc...). This discussion will draw upon recent theoretical studies based on abstract and detailed network models, with special emphasis on the issue of how the differentiation process is intimately linked to the cell-cycle and intercellular signaling processes.